Explanation 14 (E) Splenic sequestration is characteri | 👼Pediatrics. Books,Videos, MCQs...

Explanation 14







(E) Splenic sequestration is characterized by an acutely enlarging spleen and a decreasing (or decreased) hemoglobin, and frequently is associated with thrombocytopenia. Prompt
recognition and treatment is necessary because some of the severe cases will rapidly progress to shock and death. Most of these acute splenic sequestration crises occur during infancy andearly childhood and are uncommon after the fourth or fifth birthday, by which time autosplenectomy (due to recurrent infarctions) has occurred. In patients with sickle cell disease or sickle thalassemia, however, the spleen may remain large and sequestration crises can occur into the teens and adulthood