2023-05-05 18:00:12
183.Explanation
Correct Answer - B
Polycythaemia vera (PV) is a clonal disorder characterized by
increased production of all myeloid elements resulting in pancytosis
(i.e increased red cells, granulocytes, platelets) in the absence of
any recognizable cause.
The term ‘polycythemia vera’ or ‘polycythemia rubra vera’ is used
for primary or idiopathic polycythemia only and is the most common
of all the myeloproliferative disorders.
Secondary polycythemia or erythrocytosis, on the other hand, may
occur secondary to several causes e.g. high altitude, cardiovascular
disease, a pulmonary disease with alveolar hypoventilation, heavy
smoking, inappropriate increase in erythropoietin (renal cell
carcinoma, hydronephrosis, hepatocellular carcinoma, cerebellar
hemangioblastoma, massive uterine leiomyoma).
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